发明名称 |
Use of IGFBP-2 in Senescence Diseases and for the Maintenance of Organ Functions |
摘要 |
The present invention relates to the use of an IGFBP-2 (insulin-like growth factor binding protein-2) molecule for the production of a pharmaceutical composition for the regulation of senescence processes in cells, tissues and/or organs for the maintenance and control of tissue and/or organ functions and/or for the treatment or alleviation of senescence symptoms or early senescence, wherein the IGFBP-2 molecule is selected from the group of an IGFBP-2 polypeptide or of a functional fragment thereof and of a nucleic acid encoding an IGFBP-2 polypeptide or a functional fragment or derivative thereof. Moreover, corresponding methods of treatment are provided. The use of IGFBP-2 in the preparation of a pharmaceutical composition in the medical intervention of cachexia is described.
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申请公布号 |
US2010028302(A1) |
申请公布日期 |
2010.02.04 |
申请号 |
US20050663784 |
申请日期 |
2005.09.26 |
申请人 |
LUDWIG-MAXIMILIANS- UNIVERSITAET MUENCHEN |
发明人 |
HOFLICH ANDREAS;WOLF ECKHARD;RENNER-MUELLER INGRID;RENNER PETRA;DIEHL DANIELA;BIELOHUBY MAX;HESSEL ESTHER |
分类号 |
A61K35/12;A61K31/7088;A61K38/16 |
主分类号 |
A61K35/12 |
代理机构 |
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主权项 |
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地址 |
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