发明名称 |
Improved process for the production of daptomycin |
摘要 |
<p>The present invention relates to an improved process for the production of Daptomycin by fermentation with Streptomyces roseosporus, in the presence of n-decanal or Cuphea oil as sources of the n-decanoyl side chain. These reagents allow to reduce toxicity effects on the bacteria and to avoid the use of solvents in the feeding solution.</p> |
申请公布号 |
EP2149609(A1) |
申请公布日期 |
2010.02.03 |
申请号 |
EP20080161630 |
申请日期 |
2008.08.01 |
申请人 |
ANTIBIOTICOS S.P.A. |
发明人 |
BERTETTI, GIANLUCA;MALCANGI, ANTONELLA;MURACA, ROBERTO;TRIONE, GUIDO;ROSSI, ALESSIA |
分类号 |
C12P21/04 |
主分类号 |
C12P21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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