发明名称 BIR DOMAIN BINDING COMPOUNDS
摘要 The present invention is directed towards an isomer, an enantiomer, a diastereoisomer, or a tautomer of a pyrrolidine compound represented by Formula I: in which the substituents R1, R1a, R2, R2a, R3, A and Q are defined herein; or a prodrug, or a salt thereof, and which bind to IAP BIR domains. In particular, the compounds are useful in treating proliferative disorders such as cancer.
申请公布号 EP1883627(A4) 申请公布日期 2010.02.03
申请号 EP20060741509 申请日期 2006.05.16
申请人 AEGERA THERAPEUTICS INC. 发明人 LAURENT, ALAIN;JARVIS, SCOTT;BOUDREAULT, ALAIN;BUREAU, PATRICK;JAQUITH, JAMES;LABIT, DELPHINE
分类号 C07D207/08;A61K31/40;A61P35/00;C07D401/12;C07D403/12 主分类号 C07D207/08
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