Co-administration of a tissue plasminogen activator, anti-CD11b antibody and anti-CD18 antibody in stroke

摘要

A method for improving clinical outcome in focal ischemic stroke in a mammal by increasing cerebral blood flow and/or reducing infarct size is described which involves administering an effective amount of an anti-CD18 antibody to the mammal, in the absence of removal of the arterial obstruction.