发明名称 Method of using interferon-like protein ZCYTO20 (IL-28A) or ZCYTO22 (IL-28B) to treat hepatitis C
摘要 The present invention relates to polynucleotide and polypeptide molecules for zcyto20, zcyto21, zcyto22, zycto24, and zcyto25 proteins which are most closely related to interferon-alpha at the amino acid sequence level. The receptor for this protein family is a class II cytokine receptor. The present invention includes methods of reducing viral infections and increasing monocyte counts. The present invention also includes antibodies to the zcyto20 polypeptides, and methods of producing the polynucleotides and polypeptides.
申请公布号 US7655222(B2) 申请公布日期 2010.02.02
申请号 US20070868170 申请日期 2007.10.05
申请人 ZYMOGENETICS, LLC 发明人 SHEPPARD PAUL O.;FOX BRIAN A.;KLUCHER KEVIN M.;TAFT DAVID W.;KINDSVOGEL WAYNE
分类号 A61K38/20;A61K38/00;A61K38/21;C07K14/00 主分类号 A61K38/20
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