| 发明名称 |
USE OF GROUP I MGLUR ANTAGONISTS IN THE TREATMENT OF FRAGILEX SYNDROME, AUTISM, MENTAL RETARDATION |
| 摘要 |
Compositions and uses of mGluR5 antagonists for the treatment and prevention of neurological disorders, such as Fragile X, autism, mental retardation, schizophrenia and Down's Syndrome, are disclosed.
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| 申请公布号 |
CA2442478(C) |
申请公布日期 |
2010.02.02 |
| 申请号 |
CA20022442478 |
申请日期 |
2002.04.02 |
| 申请人 |
EMORY UNIVERSITY;BROWN UNIVERSITY |
发明人 |
HUBER, KIMBERLY M.;BEAR, MARK F.;WARREN, STEPHEN T. |
| 分类号 |
A61K45/08;C07D217/26;A61K31/00;A61K31/198;A61K31/44;A61K31/472;A61K31/4725;A61K45/00;A61P25/00;A61P25/18;A61P25/28;A61P43/00;C07D213/16;C07D213/76;C07D401/12 |
主分类号 |
A61K45/08 |
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