发明名称 Derivatives of 2-aminothiazoles and 2-amino-oxazoles, processes for their preparation and their use as pharmaceutical compositions
摘要 The present invention relates to derivatives of 2-aminothiazoles and 2-aminooxazoles in all its stereoisomeric forms, enantiomeric forms and mixtures in any ratio, and its physiologically acceptable salts and tautomeric forms showing peroxisome proliferators activator receptor (PPAR) delta agonist activity. These compounds are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.
申请公布号 US7655679(B2) 申请公布日期 2010.02.02
申请号 US20080055771 申请日期 2008.03.26
申请人 SANOFI-AVENTIS 发明人 KEIL STEFANIE;URMANN MATTHIAS;GLIEN MAIKE;WENDLER WOLFGANG;CHANDROSS KAREN;LEE LAN
分类号 A61K31/4025;C07D413/10 主分类号 A61K31/4025
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