发明名称 |
TRANSGENIC ANIMALS FOR ASSESSING DRUG METABOLISM AND TOXICITY |
摘要 |
<p>The present invention relates to transgenic non-human animals, tissues or cells derived therefrom and methods of producing them. The transgenic non-human animals or tissues or cells derived therefrom provide a system capable of expressing human proteins responsible for drug metabolism in place of the homologous endogenous non-human animal proteins and for the controlled expression of human genes introduced into the animal so that the expression of the human genes is regulated in a manner more closely analogous to that seen in vivo in humans. FIG 1</p> |
申请公布号 |
SG158115(A1) |
申请公布日期 |
2010.01.29 |
申请号 |
SG20090081290 |
申请日期 |
2005.12.13 |
申请人 |
ITI SCOTLAND LIMITED |
发明人 |
WOLF, CHARLES, ROLAND;SCHEER, NICO;FAUST, NICOLE |
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