| 摘要 |
THE PRESENT INVENTION RELATES GENERALLY TO AN ASSAY TO DETECT A BINDING PARTNER. THE PRESENCE OR ABSENCE OF A BINDING PARTNER CAN BE USED TO INDICATE A NORMAL CONDITION OR A DISEASE CONDITION OR DISORDER OR A PROPENSITY FOR A DISEASE CONDITION OR DISORDER TO DEVELOP OR THE PRESENCE OF A PARTICULAR CELL TYPE, OR MICROBIAL, VIRAL, PARASITIC OR OTHER PATHOGENIC AGENT IN AN ANIMAL, AVIAN SPECIES OR PLANT OR THE PRESENCE OF A PARTICULAR CHEMICAL ENTITY IN A SAMPLE SUCH AS A CHEMICAL LIBRARY, BIOLOGICAL SPECIMEN OR ENVIRONMENTAL SAMPLE OR PHAGE DISPLAY LIBRARY. THE PRESENT INVENTION FURTHER PROVIDES A DIAGNOSTIC DEVICE INCLUDING A PROGNOSTIC ASSAY FOR PARAMETERS WHICH ARE INDICATIVE OF A CONDITION OR EVENT ASSOCIATED WITH THE SYSTEMIC VASCULATURE. THE ASSAY OF THE PRESENT INVENTION IS USEFUL INTER ALIA FOR THE DETECTION OF CANCERS AND NEOPLASIAS AND TO DETECT PARAMETERS ASSOCIATED WITH A VASCULAR DISEASE INCLUDING CARDIOVASCULAR, STROKE, PULMONARY, RENOVASCULAR, CETEBROVASCULAR, THROMBOTIC OR GENERALIZED ARTERIAL OR VENOUS CONDITION OR EVENT INCLUDING ACUTE CORONARY SYNDROME SUCH AS BUT NOT LIMITED TO ACUTE MYOCARDIAL INFARCTION, HEART FAILURE, ATHEROMOMA OR A THROMBOTIC CONDITION.
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