| 发明名称 |
BASIC NON-PEPTIDE BRADYKININ ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREFROM |
| 摘要 |
<p>Non-peptide compounds of formula (I) having activity as specific antagonists of bradykinin (BK) B2 receptor. The compounds are chemically characterized by the presence of an alpha, alpha-disubstituted amino acid at least one amino group, free or salified, or the corresponding ammonium quaternary salt. These BK receptor antagonists are a novel class of medicaments which can be used in all the disorders in which the receptors are involved.</p> |
| 申请公布号 |
SI1513531(T1) |
申请公布日期 |
2010.01.29 |
| 申请号 |
SI20030031698T |
申请日期 |
2003.06.05 |
| 申请人 |
MENARINI RICERCHE S.P.A. |
发明人 |
CALVANI FEDERICO;CATRAMBONE FERNANDO;FELICETTI PATRIZIA;FINCHAM CHRISTOPHER INGO;GIOLITTI ALESSANDRO;MAGGI CARLO ALBERTO;QUARTARA LAURA;ROSSI CRISTINA;TERRACCIANO ROSA |
| 分类号 |
A61K31/47;A61K31/4709;A61K31/496;A61P1/04;A61P1/16;A61P9/00;A61P9/02;A61P9/10;A61P11/00;A61P11/06;A61P13/10;A61P13/12;A61P17/00;A61P17/06;A61P17/14;A61P19/02;A61P25/04;A61P29/00;A61P31/04;A61P35/00;A61P37/06;A61P37/08;A61P43/00;C07D215/26;C07D401/12 |
主分类号 |
A61K31/47 |
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