| 摘要 |
Disclosed is a pharmaceutical formulation comprising a)one or more NO-releasing NSAID(s) of formula (I), wherein M is selected from the pictured groups, and X is a spacer group as described in the specification; b) one or more surfactants wherein the ratio surfactant:NO-releasing NSAID is from 0.1:1 to 10:1; and c) carbonyl scavenger compound selected from free acid forms, salts, carboxylic acid esters derivatives of a compound of formula (II), wherein m is between 0 and 10, and wherein the amount of the compound of formula (II) is from about 0.01% to about 5% by weight of the total weight of the composition.
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