ANALYSIS AND RESIDUE DETERMINATION METHOD OF ANTIBIOTICS IN THE LIQUID BIO-SAMPLES

摘要

PURPOSE: A method for detecting antibiotics remaining in bio sample is provided to simplify process using general extraction container and reduce discharge of contamination pollutant. CONSTITUTION: A method for detecting antibiotics contained in liquid bio sample using SFE(supercritical fluid extraction) comprises: a step of inserting absorption member into SFE extraction container; a step of absorbing liquid bio sample in the absorption member; and a step of extracting fluoroquinolone antibiotics contained in bio sample under process condition. The process condition is 20-30% of extraction aid content, 120-150°C, 250-320kg/cm^2 and extraction time 20-40. The fluoroquinolone antibiotics are orbifloxacin.