| 发明名称 |
COMBINATION OF CYTOCHOME P 450 DEPENDENT PROTEASE INHIBITORS |
| 摘要 |
<p>The present invention relates to a method for improving the pharmacokinetics of hexahydrofuro[2,3-b]furanyl containing HIV protease inhibitors comprising administering to a human in need thereof a combination of a therapeutically effective amount of a hexahydrofuro[2,3-b]furanyl containing HIV protease inhibitor, and a therapeutically effective amount of a cytochrome P<SUB>450 </SUB>inhibitor.</p> |
| 申请公布号 |
SI1458447(T1) |
申请公布日期 |
2010.01.29 |
| 申请号 |
SI20020030865T |
申请日期 |
2002.12.12 |
| 申请人 |
TIBOTEC PHARMACEUTICALS LTD. |
发明人 |
VAN DER GEEST RONALD;STOFFELS PAUL;GROEN CORNELIS;JOCHMANS DIRK EDWARD DESIRE |
| 分类号 |
C07D493/04;A61K31/34;A61K31/365;A61K31/4164;A61K31/427;A61K31/496;A61K31/635;A61K45/00;A61P31/12;A61P31/18;A61P43/00 |
主分类号 |
C07D493/04 |
| 代理机构 |
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