发明名称 N4-PHENYL-QUINAZOLINE-4 -AMINE DERIVATIVES AND RELATED COMPOUNDS AS ERBB TYPE I RECEPTOR TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES
摘要 This invention provides compounds of Formula (I), wherein B, G, A, E, R 1 , R 2 , R 3 , m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.
申请公布号 PT1971601(E) 申请公布日期 2010.01.26
申请号 PT20060837728T 申请日期 2006.11.15
申请人 ARRAY BIOPHARMA INC. 发明人 JOSEPH P. LYSSIKATOS;FREDRIK P. MARMSATER;QIAN ZHAO;JULIE MARIE GRESCHUK
分类号 C07D413/14;A61K31/517;A61P35/00;C07D401/14;C07D403/12;C07D403/14;C07D413/12;C07D417/12;C07D417/14;C07D471/04;C07D495/04 主分类号 C07D413/14
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