发明名称 Activator of peroxisome proliferator-activated receptor delta
摘要 A compound represented by the following general formula (I): (wherein R1 represents phenyl, etc. which can have substituents selected from the group consisting of C1-8 alkyl, C1-8 alkyl having halogen, halogen, hydroxyl, etc.; R2 represents C1-8 alkyl, etc.; A represents oxygen, sulfur, etc.; X represents C1-8 alkylene chain, etc.; Y represents C(-O), CH-CH, etc.; R3, R4, and R5 each represents hydrogen, C1-8 alkyl, etc.; B represents CH or nitrogen; Z represents oxygen or sulfur; R6 and R7 each represents hydrogen, C1-8 alkyl, etc.; and R8 represents hydrogen or C1-8 alkyl; provided that at least one of R3, R4, and R5 is not hydrogen) or a salt of the compound; and a PPAR-delta activator which contains the compound or salt as the active ingredient.
申请公布号 US7652045(B2) 申请公布日期 2010.01.26
申请号 US20070888493 申请日期 2007.07.31
申请人 NIPPON CHEMIPHAR, CO., LTD. 发明人 SAKUMA SHOGO;YAMAKAWA TOMIO;KANDA TAKASHI;MASUI SEIICHIRO
分类号 A61K31/421;A61K31/426;A61P3/04;A61P3/06;A61P3/10;A61P5/14;A61P9/00;A61P9/10;A61P19/10;A61P21/04;A61P25/28;A61P31/00;A61P35/00;A61P43/00;C07D233/54;C07D263/30;C07D263/32;C07D263/62;C07D277/20;C07D277/24;C07D277/26 主分类号 A61K31/421
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