发明名称 |
Polyelectrolytic internal calibration system of a flow-through assay |
摘要 |
A flow-through assay for detecting the quantity of an analyte residing in a test sample is provided. The flow-through assay contains a porous membrane that is in fluid communication with probe conjugates that contain a specific binding member and a detectable probe. The porous membrane also defines a detection zone and a calibration zone. The calibration zone contains a polyelectrolyte substantially non-diffusively immobilized on the porous membrane. The polyelectrolyte is capable of generating a detectable calibration signal that can be readily compared (visually, quantitatively, and the like) to a detection signal to determine the amount of analyte in the test sample.
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申请公布号 |
US7651841(B2) |
申请公布日期 |
2010.01.26 |
申请号 |
US20020132421 |
申请日期 |
2002.04.25 |
申请人 |
KIMBERLY-CLARK WORLDWIDE, INC. |
发明人 |
SONG XUEDONG;WEI NING;SAYRE CURT |
分类号 |
G01N33/53;C12M1/34;C12M3/00;C12Q1/50;G01N21/77;G01N31/22;G01N33/00;G01N33/543;G01N33/546;G01N33/558;G01N33/566 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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