发明名称 |
Method of preparing clopidogrel and intermediates used therein |
摘要 |
Optically pure clopidogrel can be prepared in a high yield by optically resolving a racemic form of the compound of formula (II) using an optically active amine to form the optically active form of the compound of formula (III) or its acid-addition salt; and methylating the compound of formula (III) or its acid-addition salt.
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申请公布号 |
US7652140(B2) |
申请公布日期 |
2010.01.26 |
申请号 |
US20050917794 |
申请日期 |
2005.11.28 |
申请人 |
HANMI PHARM. CO., LTD |
发明人 |
KIM EUN SOOK;KIM HEE CHEOL;KWON BO SUNG;YUN SANGMIN;KO MI YOUNG;KIM CHEOL KYUNG;SUH KWEE HYUN |
分类号 |
C07D495/04 |
主分类号 |
C07D495/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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