发明名称 BICYCLOANILINE DERIVATIVE.
摘要 <p>Disclosed are: a compound represented by the general formula (I); and others. (I) wherein A<sup>1</sup> and A<sup>2</sup> independently represent a nitrogen atom or a methine group which may be substituted; the ring B represents a 5- to 7-membered aliphatic ring or a spiro or bicyclo ring formed by the aliphatic ring and a 3- to 7-membered aliphatic ring which is different from the aforementioned aliphatic ring; R<sup>1</sup> represents a hydrogen atom, a C1-C6 alkyl group which may be substituted or an aryl, aralkyl or heteroaryl group which may be substituted; R<sup>2</sup> represents an aryl, aralkyl or heteroaryl group which may be substituted; and X represents a group represented by the formula =NH or =O. The compound has an excellent cell proliferation inhibition activity relying on a Wee1 kinase inhibition activity and an additive/synergistic effect with other anti-cancer agent, and is therefore useful in the medical field.</p>
申请公布号 MX2009013728(A) 申请公布日期 2010.01.25
申请号 MX20090013728 申请日期 2008.06.12
申请人 BANYU PHARMACEUTICAL CO., LTD. 发明人 BAMBA, MAKOTO;TAKAHASHI, KEIJI;NIIYAMA, KENJI;SAKAMOTO, TOSHIHIRO;SUNAMI, SATOSHI;YAMAMOTO, FUYUKI;FURUYAMA, HIDETOMO;YOSHIZUMI, TAKASHI
分类号 C07D487/04;A61K31/522;A61K31/5415;A61K31/55;A61K31/553;A61K45/00;A61P35/00;A61P43/00;C07D519/00 主分类号 C07D487/04
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