发明名称 |
STABLE SOLID PREPARATION COMPRISING 4,5-EPOXYMORPHINAN DERIVATIVE. |
摘要 |
<p>Disclosed is a stable solid preparation comprising a 4,5-epoxymorphinan derivative or a pharmacologically acceptable acid addition salt thereof as an active ingredient. Specifically disclosed is a stable solid preparation comprising: a 4,5-epoxymorphinan derivative represented by the general formula (I) or a pharmacologically acceptable acid addition salt thereof as an active ingredient; sodium thiophosphate; a sugar or a sugar alcohol; and a hydroxypropylcellulose having a low degree of substitution in an amount of 1 to 30% by weight per unit weight of the total amount of the active ingredient, sodium thiophosphate and the sugar or the sugar alcohol.</p> |
申请公布号 |
MX2009011554(A) |
申请公布日期 |
2010.01.25 |
申请号 |
MX20090011554 |
申请日期 |
2008.04.25 |
申请人 |
TORAY INDUSTRIES, INC. |
发明人 |
KOTOE OHTA;SUGURU TAKAKI;YASUHIDE HORIUCHI;MASATO KOBAYASHI;JUNKO KAWASAKI;EIJIRO HORISAWA |
分类号 |
A61K31/485;A61K9/14;A61K9/16;A61K9/20;A61K9/28;A61K9/48;A61K47/02;A61K47/10;A61K47/26;A61K47/36;A61K47/38;A61P11/14;A61P17/04;A61P25/02 |
主分类号 |
A61K31/485 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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