| 摘要 |
PROBLEM TO BE SOLVED: To provide an anti-inflammatory agent which can efficiently suppress inflammation and is highly safe with little side effect. SOLUTION: The anti-inflammatory agent contains 4-amino-6-hydroxypyrazolo(3,4-d)pyrimidine, its pharmaceutically acceptable salt, its derivative, or a micelle containing 4-amino-6-hydroxypyrazolo(3,4-d)pyrimidine. Combining 4-amino-6-hydroxypyrazolo(3,4-d)pyrimidine with a polymer such as a styrene-maleic acid copolymer, PEG, polyacrylic acid, and polyvinylacetic acid improves water solubility and retention in blood and allows the resulting anti-inflammatory agent to be more efficiently accumulated in a focus to thereby reduce side effect. COPYRIGHT: (C)2010,JPO&INPIT |
