发明名称 |
HCV/GBV-B chimeric virus |
摘要 |
<p>An HCV/GBV-B chimeric virus which maintains the replication function of HCV and is capable of infecting tamarin is disclosed in order to construct an HCV animal model which can be used as a development or evaluation system for therapeutic agents for HCV. The HCV/GBV-B chimeric RNA comprises an RNA of hepatitis C virus and an RNA of GB virus-B, wherein the RNA of hepatitis C virus comprises an RNA encoding leucine at the 1804th position and lysine at the 1966th position in the amino acid sequence of the polyprotein of hepatitis C virus.</p> |
申请公布号 |
AU2009273061(A1) |
申请公布日期 |
2010.01.21 |
申请号 |
AU20090273061 |
申请日期 |
2009.07.15 |
申请人 |
ADVANCED LIFE SCIENCE INSTITUTE, INC. |
发明人 |
NOBORU MAKI;KENICHI MORI;HIROMI FUKAI |
分类号 |
C12N15/09;A01K67/027;C07K14/18;C07K19/00;C12N5/10;C12N7/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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