| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a nucleic acid analyzing device, capable of completing the preparation of analysis, in a short time and at low cost, by enhancing the specific bonding speed between a target molecule in a specimen and a probe molecule while specifically bonding a nucleic acid probe to the fluorescent enhanced field generating region on a metallic structure on a substrate. Ž<P>SOLUTION: While a substrate having a metallic structure is irradiated with light, high-frequency AC voltage is applied between two plate electrodes which are arranged so as to sandwitch the substrate. By irradiating the substrate with the a light for generating a localized type surface plasmon on the metallic structure on the substrate, and by applying the high-frequency AC voltage to produce electric field distribution, the nucleic acid probe and the nucleic acid specimen are specifically guided to a position where strong electric field exists, namely, the fluorescent enhanced field by utilizing dielectrophoresis. By utilizing this effect, the hybridization speed between the nucleic acid probe and the specimen nucleic acid is enhanced, while bonding the nucleic acid probe molecule to the specific microposition (fluorescent enhanced field generating region) on the metallic structure. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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