摘要 |
The present invention relates to the use of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular argyrin and derivatives thereof, for a treatment in a variety of conditions, such as the induction of immunotolerance, autoimmune diseases, bacterial infections, and proliferative diseases, such as cancers. |
申请人 |
HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH;MEDIZINISCHE HOCHSCHULE HANNOVER;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER;KALESSE, MARKUS;MALEK, NISAR;FRANK, RONALD;BRODMANN, TOBIAS;BUELOW, LEILA;RENTSCH, ANDREAS;GIRBIG, ANNA-KATHARINA;EGGERT, ULRIKE |
发明人 |
KALESSE, MARKUS;MALEK, NISAR;FRANK, RONALD;BRODMANN, TOBIAS;BUELOW, LEILA;RENTSCH, ANDREAS;GIRBIG, ANNA-KATHARINA;EGGERT, ULRIKE |