| 发明名称 |
APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS |
| 摘要 |
<p>The present invention relates to apoptosis signal-regulating kinase 1 ("ASK1") inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.</p> |
| 申请公布号 |
WO2010008843(A1) |
申请公布日期 |
2010.01.21 |
| 申请号 |
WO2009US48288 |
申请日期 |
2009.06.23 |
| 申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED;CHANG, EDCON;GWALTNEY, STEPHEN L.;VASSAR, ANGIE |
发明人 |
CHANG, EDCON;GWALTNEY, STEPHEN L.;VASSAR, ANGIE |
| 分类号 |
C07D513/04;A61K31/437;A61K31/519;A61P3/00;A61P9/00;A61P11/00;A61P25/00;A61P29/00;A61P35/00;A61P37/00 |
主分类号 |
C07D513/04 |
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