发明名称 CYCLOHEXENYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
摘要 The present application describes modulators of MCP-1 or CCR-2 of formula (I), or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein T, W, X, Y, Z, R1, R2, R4 and R6, are defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula (I), are disclosed.
申请公布号 WO2010009068(A2) 申请公布日期 2010.01.21
申请号 WO2009US50449 申请日期 2009.07.14
申请人 BRISTOL-MYERS SQUIBB COMPANY;CARTER, PERCY, H.;BROWN, GREGORY, D.;DE LUCCA, GEORGE, V.;BATT, DOUGLAS, G.;LIU, RUI-QIN;QIU, FENG 发明人 CARTER, PERCY, H.;BROWN, GREGORY, D.;DE LUCCA, GEORGE, V.;BATT, DOUGLAS, G.;LIU, RUI-QIN;QIU, FENG
分类号 C07C61/15;A61K31/18;A61K31/192;A61P9/12;A61P11/06;A61P19/02;A61P31/18;C07C61/28;C07C61/39;C07C61/40;C07C62/32;C07C62/34;C07C233/47;C07C311/51 主分类号 C07C61/15
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