发明名称 |
SILICON DIOXIDE NANOPARTICLES AND THE USE THEREOF FOR VACCINATION |
摘要 |
The invention relates to ultra-small, monodisperse nanoparticles of silicon dioxide with at least one antigen attached to their surface. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also provides a method of targeting antigens at antigen-presenting cells and of activating the immune system, the efficiency of targeting and/or immune activation being adjusted via the particle characteristics. The invention also relates to methods of active and passive immunization of a mammal. |
申请公布号 |
CA2730694(A1) |
申请公布日期 |
2010.01.21 |
申请号 |
CA20092730694 |
申请日期 |
2009.07.13 |
申请人 |
MERCK PATENT GMBH |
发明人 |
WEIGANDT, MARKUS;HANEFELD, ANDREA;KUEBELBECK, ARMIN;LARBIG, GREGOR |
分类号 |
A61K9/16 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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