发明名称 PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS
摘要 Novel compounds of structure Formula (I) or an enantiomer, a diastereomer, or a pharmaceutically acceptable salt thereof, wherein Z, R1, R2, R21, T1, T2, T3 and T4 are defined herein, are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the GPR119 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.
申请公布号 CA2730929(A1) 申请公布日期 2010.01.21
申请号 CA20092730929 申请日期 2009.07.15
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 WACKER, DEAN A.;ROSSI, KAREN A.;WANG, YING;WU, GANG
分类号 C07D401/12;A61K31/4545;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P19/08;A61P25/02;A61P25/28;A61P31/00;A61P35/00;C07D401/14;C07D413/14 主分类号 C07D401/12
代理机构 代理人
主权项
地址