发明名称 |
AMINOTETRAHYDROINDAZOLOACETIC ACIDS |
摘要 |
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Q, W, X, R1-R5 and n are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
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申请公布号 |
CA2730390(A1) |
申请公布日期 |
2010.01.21 |
申请号 |
CA20092730390 |
申请日期 |
2009.07.06 |
申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
CHEN, LI;FIROOZNIA, FARIBORZ;GILLESPIE, PAUL;HE, YUN;LIN, TAI-AN;SO, SUNG-SAU;YUN, HONGYING;ZHANG, ZHENSHAN |
分类号 |
C07D231/56;A61K31/416;A61P11/06;C07D401/12;C07D413/12 |
主分类号 |
C07D231/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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