发明名称 XANTHINE-BASED CYCLIC GMP-ENHANCING RHO-KINASE INHIBITOR INHIBITS PHYSIOLOGICAL ACTIVITIES OF LUNG EPITHELIAL CELL LINE
摘要 The present invention provides a pharmaceutical composition including a compound of 7-[2-[4-(2-chlorophenyl)piperazinyl]-ethyl]-1,3-dimethylxanthine (KMUP-1), wherein the compound is a Rho-kinase inhibitor, and the pharmaceutical composition inhibits a physiological activity of a lung epithelial cell.
申请公布号 US2010016329(A1) 申请公布日期 2010.01.21
申请号 US20080176607 申请日期 2008.07.21
申请人 KAOHSIUNG MEDICAL UNIVERSITY 发明人 CHEN ING-JUN
分类号 A61K31/496;A61P35/00;C07D473/04 主分类号 A61K31/496
代理机构 代理人
主权项
地址