TAYLOR VORTEX FLOW BIOREACTOR FOR CELL CULTURE

摘要

The invention concerns a rotating wall vessel bioreactor (100) using Taylor vortex flow for cell culture in the annular space between the two concentric cylindrical bodies, wherein the internal one (2) is rotating and the external one (1 ) is stationary. The internal rotating body (2) is composed of an external wall around which a polymeric tubular membrane (6) is wrapped, which is connected to the hollow tubular axis (5) of the internal body (2) for the introduction of gases into the annular space (d). Said annular space (d) is filled with a suspension of cells or cells immobilized on microcarriers.