发明名称 |
PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS |
摘要 |
<p>Novel compounds of structure Formula (I) or an enantiomer, a diastereomer, or a pharmaceutically acceptable salt thereof, wherein Z, R1, R2, R21, T1, T2, T3 and T4 are defined herein, are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the GPR119 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.</p> |
申请公布号 |
WO2010009183(A1) |
申请公布日期 |
2010.01.21 |
申请号 |
WO2009US50618 |
申请日期 |
2009.07.15 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY;WACKER, DEAN, A.;ROSSI, KAREN, A.;WANG, YING;WU, GANG |
发明人 |
WACKER, DEAN, A.;ROSSI, KAREN, A.;WANG, YING;WU, GANG |
分类号 |
C07D401/12;A61K31/4545;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P19/08;A61P25/02;A61P25/28;A61P31/00;A61P35/00;C07D401/14;C07D413/14 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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