发明名称 PIPERIDYL ACRYLAMIDE ANTOGONISTS OF CCR2
摘要 <p>The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5 and X are as defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is uveitis, including acute, recurring or chronic uveitis. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.</p>
申请公布号 WO2010008761(A1) 申请公布日期 2010.01.21
申请号 WO2009US47895 申请日期 2009.06.19
申请人 JANSSEN PHARMACEUTICA NV;CAI, CHAOZHONG;SUI, ZHIHUA 发明人 CAI, CHAOZHONG;SUI, ZHIHUA
分类号 C07D209/14;A61K31/33;A61P19/00;C07D403/12 主分类号 C07D209/14
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