<p>A room temperature stable and minimal aggregate liquid formulation comprises an oligonucleotide comprising Seq ID No. 1: or comprising a variant oligonucleotide in which no more than 3 non-sequential bases are different from Seq. ID NO. 1 and an aqueous carrier comprising a aggregation-preventing compound selected from the group consisting of mono and disaccharides and/or sugar alcohols.</p>
申请公布号
WO2010009038(A2)
申请公布日期
2010.01.21
申请号
WO2009US50382
申请日期
2009.07.13
申请人
ONCOGENEX TECHNOLOGIES INC.;HAYES, THOMAS, K.;KRILLA, NICOLE, D.;NIXON, LORI