ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS
摘要
<p>The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.</p>
申请公布号
CA2727915(A1)
申请公布日期
2010.01.21
申请号
CA20092727915
申请日期
2009.07.14
申请人
GENENTECH, INC.;NERVIANO MEDICAL SCIENCES S.R.L.
发明人
BERIA, ITALO;CARUSO, MICHELE;FLYGARE, JOHN A.;LUPI, VITTORIA;PEREGO, RITA;POLAKIS, PAUL;POLSON, ANDREW;SALSA, MATTEO;SPENCER, SUSAN D.;VALSASINA, BARBARA