发明名称 Heteroaryl derivatives as DGAT1 inhibitors
摘要 The invention relates to compounds of formula (I): where A is selected from: and R 1 , R 2 , R 3 , R 4 , R 5 , R 10a , R 10b , M, Z, r and s are as defined in the description, useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), for example glucose tolerance, Type II diabetes or obesity. The invention also provides pharmaceutical compositions comprising such compounds.
申请公布号 AU2009272826(A1) 申请公布日期 2010.01.21
申请号 AU20090272826 申请日期 2009.07.14
申请人 NOVARTIS AG 发明人 BING WANG;KATSUMASA NAKAJIMA;CORNELIA JUTTA FORSTER;YOUNG-SHIN KWAK
分类号 A61P3/10;A61K31/427;A61P3/04;C07D213/75;C07D231/40;C07D249/14;C07D277/46;C07D401/12;C07D403/12;C07D413/12;C07D417/04;C07D417/06;C07D417/12;C07D417/14;C07D471/10 主分类号 A61P3/10
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