| 摘要 |
Cytotoxic 1-acylaziridine oximes of general formulawherein:Ar is selected from phenyl, pyridyl, quinolyl, pyrimidinyl and benztiazolyl group and is optionally substituted by an alkyl or halogen,X is O or S,n is an integer from 3 to 6,R is hydrogen, methyl or benzyl,their stereoisomers and pharmaceutically acceptable acid addition salts, where possible. |
| 申请人 |
LATVIJAS ORGANISK&Amacr,S SINT&Emacr,ZES INSTIT&Umacr,TS |
发明人 |
&Amacr,BELE EDGARS;&Amacr,BELE RAMONA;BRID&Amacr,NE VERONIKA;DOMRA&Ccaron,EVA ILONA;GOLOMBA &Lcedil,ENA;GRIGORJEVA ANNA;JAS&Ccaron,ENKO EL&Imacr,NA;JIRGENSONS AIGARS;KALVI&Ncedil,&Scaron, IVARS;&Scaron,ESTAKOVA IRINA |
