摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine and concerns methods and compositions for inducing apoptosis of cancer cells. Substance of the invention includes the modified antibodies-DR-5 agonists which in combination with apoptosis-inducing agents, synergetically induce apoptosis of cancer cells. ^ EFFECT: intensified antineoplastic activity. ^ 19 cl, 51 ex, 2 tbl, 35 dwg |