发明名称 METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS OF CANCER CELLS
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to medicine and concerns methods and compositions for inducing apoptosis of cancer cells. Substance of the invention includes the modified antibodies-DR-5 agonists which in combination with apoptosis-inducing agents, synergetically induce apoptosis of cancer cells. ^ EFFECT: intensified antineoplastic activity. ^ 19 cl, 51 ex, 2 tbl, 35 dwg
申请公布号 RU2379056(C2) 申请公布日期 2010.01.20
申请号 RU20050120167 申请日期 2003.11.25
申请人 AJRM LLS 发明人 MARK NASOFF;KVINN DEVEROKS L.;DEBORA KNI A.;PEDRO ASA-BLANK;GARRET KHEHMPTON M.;KLAUS VAGNER
分类号 A61K39/395;A61P35/00;C07K16/28;C12Q1/68 主分类号 A61K39/395
代理机构 代理人
主权项
地址