| 摘要 |
FIELD: medicine. ^ SUBSTANCE: claimed invention relates to transdermal plaster, which contains rasagiline, for treatment or prevention of nervous system diseases, where plaster contains inert supporting layer, which is chemically inert to substrate ingredients, substrate layer, which contains effective amount of rasagiline or its pharmaceutically acceptable salt, and protective layer, which is removed before application. Substrate layer represents adhesive system, which contains organic polymer material as base and inorganic or organic material as filler and many microreservoirs which contain rasagiline. Substrate additionally contains one or more substances for increase of transdermal absorption of rasagiline, where said organic polymer material in substrate is applied rasagiline reservoir and as binding substance. ^ EFFECT: increase of transdermal plaster efficiency. ^ 14 cl, 18 dwg, 26 tbl, 10 ex |
