发明名称 |
Allergy vaccine composition, production method thereof and use of same in allergy treatment |
摘要 |
The present invention relates to the field of Immunology, specifically with the branch of Immuno-Allergy and in particular with the use of adjuvant or carrier compounds, capable of modulating the immune response to allergens. The technical objective that is pursued is to obtain a pharmaceutical preparation of therapeutic or prophylactic use using bacterial proteoliposomes, which transform the allergic response Th2 and IgE when being applied in allergic individuals, toward a protector response Th1; as well as it is able to prevent the appearance and the development of allergies in individuals non-allergic yet. The vaccine composition consists of proteoliposomes derived from Gram-negative bacteria coupled to allergens and optionally contains other adjuvants or antigens. The method for its preparation and an immunization scheme of two doses are provided.
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申请公布号 |
US7648709(B2) |
申请公布日期 |
2010.01.19 |
申请号 |
US20030513493 |
申请日期 |
2003.05.08 |
申请人 |
LASTRE GONZALEZ MIRIAM DE SAN;PEREZ MARTIN OLIVER GERMAN;LABRADA ROSADO ALEXIS;BIDOT MARTINEZ IGOR;BRACHO GRANADO GUSTAVO RAFAEL;DEL CAMPO ALONSO JUDITH MONICA;PEREZ LASTRE DAINERYS ALEIDA;FACENDA RAMOS ELISA;ZAYAS VIGNIER CARIDAD;RODRIGUEZ MARTINEZ CLAUDIO;SIERRA GONZALEZ VICTORIANO GUSTAVO;PEREZ LASTRE JORGE ERNESTO |
发明人 |
LASTRE GONZALEZ MIRIAM DE SAN JUAN BOSCO;PEREZ MARTIN OLIVER GERMAN;LABRADA ROSADO ALEXIS;BIDOT MARTINEZ IGOR;BRACHO GRANADO GUSTAVO RAFAEL;DEL CAMPO ALONSO JUDITH MONICA;PEREZ LASTRE DAINERYS ALEIDA;FACENDA RAMOS ELISA;ZAYAS VIGNIER CARIDAD;RODRIGUEZ MARTINEZ CLAUDIO;SIERRA GONZALEZ VICTORIANO GUSTAVO;PEREZ LASTRE JORGE ERNESTO |
分类号 |
A61K39/095;A61K39/35 |
主分类号 |
A61K39/095 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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