摘要 |
Compounds of formula (I) inhibit HDAC activity, wherein A, B and D independently represent -C- or -N-; W is a divalent radical -CH-CH- or CH2CH2-; R1 is a carboxylic acid group (-COOH), or an ester group which is hydrolysable by one or more intracellular carboxyesterase enzymes to a carboxylic acid group; R2 is the side chain of a natural or non-natural alpha amino acid; z is 0 or 1; and Y, L1, and X1 are as defined in the claims.
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