发明名称 HDAC INHIBITORS
摘要 Compounds of formula (I) inhibit HDAC activity, wherein A, B and D independently represent -C- or -N-; W is a divalent radical -CH-CH- or CH2CH2-; R1 is a carboxylic acid group (-COOH), or an ester group which is hydrolysable by one or more intracellular carboxyesterase enzymes to a carboxylic acid group; R2 is the side chain of a natural or non-natural alpha amino acid; z is 0 or 1; and Y, L1, and X1 are as defined in the claims.
申请公布号 US2010010010(A1) 申请公布日期 2010.01.14
申请号 US20070443096 申请日期 2007.09.14
申请人 CHROMA THERAPEUTICS LTD. 发明人 DAVIDSON ALAN HORNSBY;MOFFAT DAVID FESTUS CHARLES;DAY FRANCESCA ANN;DONALD ALASTAIR DAVID GRAHAM
分类号 A61K31/4965;A61K31/235;A61K31/445;A61P35/00;C07C229/32;C07D211/56;C07D241/04 主分类号 A61K31/4965
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