摘要 |
<p>According to one aspect of the invention, there is provided a method of extending the shelf-life of a pharmaceutically acceptable opioid agonist composition, such as a fentanyl or fentanyl citrate composition, said method comprising maintaining the composition at a pH value in a range of between 3.8 and 6.5, between 4.5 and 6.3, between 5.0 and 6.2, or at a pH value of about 6.0.</p> |