发明名称 PROCESS FOR THE PREPARATION OF PURE 4'-[4-METHYL-6-(1-METHYL-2-BENZIMIDAZOLYL)-2-PROPYL-1-BENZIMIDAZOLYL]METHYL]-2-BIPHENYLCARBOXYLIC ACID
摘要 <p>The present invention relates to the purification of Telmisartan (I) from a mixture of water immiscible solvent and polar aprotic solvent, which results in the Telmisartan with the purity of above 99.5% by HPLC. Further, the precipitation process of the present invention improves flowability of crystallized product, ease of filtration from the crystalline medium, thereby increasing the yield, decreasing the cost and avoiding the drying problems.</p>
申请公布号 WO2010004385(A1) 申请公布日期 2010.01.14
申请号 WO2009IB05934 申请日期 2009.06.15
申请人 AUROBINDO PHARMA LIMITED;KORRAPATI, VENKATA VARA PRASADA RAO;INTI, VENKATA SUBRAMANYESWARA RAO;ANANTA, RANI;MEENAKSHISUNDERAM, SIVAKUMARAN 发明人 KORRAPATI, VENKATA VARA PRASADA RAO;INTI, VENKATA SUBRAMANYESWARA RAO;ANANTA, RANI;MEENAKSHISUNDERAM, SIVAKUMARAN
分类号 C07D235/20;A61K31/4184;A61P9/00 主分类号 C07D235/20
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