POLYPEPTIDES INVOLVED IN THE NEUROREGENERATION-PROMOTING PROPERTIES OF OLFACTORY ENSHEATHING GLIA
摘要
The present invention relates to methods for promoting regeneration response of primary olfactory nervous system in mammals in need of such biological effects. The methods comprise altering the activity or steady state level of a polypeptide as defined herein that control regeneration of injured or degenerated neuronal cells. Preferably the activity or steady state level of said polypeptide is altered by introducing nucleic acids to increase expressing of at least one of these polypeptides. These are useful in or suffering from neurotraumatic injury such as spinal cord injury.
申请公布号
CA2726945(A1)
申请公布日期
2010.01.14
申请号
CA20092726945
申请日期
2009.06.16
申请人
NEDERLANDS INSTITUUT VOOR NEUROWETENSCHAPPEN
发明人
VERHAAGEN, JOOST;FRANSSEN, ELSKE HELENA PHILOMENA;DE BREE, FREDERIK MARCO;SMIT, AUGUST BENJAMIN;VAN KESTEREN, RONALD ERNST