发明名称 CRYSTALLINE MESOPOROUS OXIDE BASED MATERIALS USEFUL FOR THE FIXATION AND CONTROLLED RELEASE OF DRUGS
摘要 The invention describes a new class of crystalline silica material having two levels of porosity and structural order. At the first level, building units are nanoslabs of uniform size having zeolite framework. At the second structural level, nanoslabs are assembled, e.g. linked through their corners, edges or faces following patterns imposed by interaction with cationic surfactant or triblock copolymer molecules. After evacuation of these molecules, microporosity is obtained inside the nanoslabs, and a precise mesoporosity between the nanoslabs depending on the tiling pattern of the zeolite nanoslabs, as evidenced by X-ray diffraction. These materials are useful for the fixation of biologically active species, such as poorly soluble drugs.
申请公布号 US2010008990(A1) 申请公布日期 2010.01.14
申请号 US20090498015 申请日期 2009.07.06
申请人 K.U. LEUVEN RESEARCH & DEVELOPMENT 发明人 MARTENS JOHAN ADRIAAN;ANTONIA KIRSCHHOCK CHRISTINE EVA;BRIGITTE KREMER SEBASTIEN PHILIPPE;EUGEEN AERTS ALEXANDER JAN MARIA HERMAN;MOOTER GUY VAN DEN;HUMBEECK JAN VAN
分类号 A61K31/496;A61K9/10;A61K31/5513;A61P25/22;C01B39/02;C01B39/04 主分类号 A61K31/496
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