发明名称 |
PROTEASE RESISTANT INSULIN ANALOGUES |
摘要 |
The present invention relates to novel insulin analogues exhibiting resistance towards protease, wherein at least two amino acids are substituted and/or deleted relative to the parent insulin molecule. A method for the preparation of such insulin analogues, insulin preparations containing the insulin analogues of the invention and a method of treating diabetes mellitus using these insulin analogues is also provided.
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申请公布号 |
US2010009898(A1) |
申请公布日期 |
2010.01.14 |
申请号 |
US20070442190 |
申请日期 |
2007.09.20 |
申请人 |
NIELSEN PETER KRESTEN;HUBALEK FRANTISEK;LAUTRUP-LARSEN INGER;LUDVIGSEN SVEND;RIBEL-MADSEN ULLA;BALSCHMIDT PER;NORGAARD PER;HAVELUND SVEND |
发明人 |
NIELSEN PETER KRESTEN;HUBALEK FRANTISEK;LAUTRUP-LARSEN INGER;LUDVIGSEN SVEND;RIBEL-MADSEN ULLA;BALSCHMIDT PER;NORGAARD PER;HAVELUND SVEND |
分类号 |
A61K38/28;C07K14/62;C12N15/11 |
主分类号 |
A61K38/28 |
代理机构 |
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地址 |
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