发明名称 |
VARIABLE DOMAINS OF CAMELID HEAVY-CHAIN ANTIBODIES DIRECTED AGAINST GLIAL FIBRILLARY ACIDIC PROTEINS |
摘要 |
The present invention relates to the use of variable domains of camelid heavy-chain antibodies (VHH domains) directed against an intracellular target and having an isoelectric point of at least 8.5, for targeting said intracellular target or for the preparation of a peptide vector. Particularly, it concerns VHH domains directed against a glial fibrillary acidic protein and uses thereof for preparing therapeutic or diagnostic agents. |
申请公布号 |
CA2730268(A1) |
申请公布日期 |
2010.01.14 |
申请号 |
CA20092730268 |
申请日期 |
2009.07.10 |
申请人 |
INSTITUT PASTEUR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
LAFAYE, PIERRE;BOURGEOIS, JEAN-PIERRE;ROUGEON, FRANCOIS |
分类号 |
C07K16/30;A61K39/395 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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