METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS
摘要
The present invention provides compositions comprising antisense nucleic acids that reduce miR-126 levels in an endothelial cell. The present invention provides compositions comprising a target protector nucleic acid. The present invention provides methods of modulating angiogenesis in an individual, the methods generally involving administering to the individual an effective amount of an agent that increases or that decreases the level of miR-126 in endothelial cells of the individual.
申请公布号
WO2010005850(A1)
申请公布日期
2010.01.14
申请号
WO2009US49438
申请日期
2009.07.01
申请人
THE J. DAVID GLADSTONE INSTITUTES;FISH, JASON, E.;SRIVASTAVA, DEEPAK