COMPOSITIONS AND METHODS FOR PROPHYLAXIS AND TREATMENT OF CELLULAR DEGENERATIVE DISORDERS

摘要

The present application relates to novel therapeutic strategies for cellular degenerative ophthalmic diseases, and more specifically diseases associated with photoreceptor degeneration, such as age-related macular degeneration, retinitis pigmentosa, macular and retinal edema and uveitis. The invention relates to a novel use of 4EBPs modulators, and more specifically of 4EBPs inhibitors. The compounds of the invention are useful for the preparation of pharmaceutical compositions for prophylaxis and treatment of cellular degenerative ophthalmic diseases, and more specifically neurodegenerative disorders.