发明名称 |
BUFFERED SWELLING MEDIA FOR RADIATION STERILIZED HYDROPHILIC COATINGS |
摘要 |
To identify an alternative swelling medium with a hydrophilic polymer, we have observed that a swelling medium containing only 6 % PEG 2000 and 0.9 % NaCl failed to protect a hydrophilic coating during electron beam sterilization and subsequent storage at ambient and higher temperatures in an accelerated storage stability test. An unacceptably low dry- out time, below the specified 5 minutes, was obtained. However, when the biological buffer sodium citrate was added to a swelling medium containing PEG 2000, the performance of the stored catheters was as good as or better than the performance of catheters stored with the conventional swelling medium. |
申请公布号 |
WO2010003419(A2) |
申请公布日期 |
2010.01.14 |
申请号 |
WO2009DK50130 |
申请日期 |
2009.06.16 |
申请人 |
COLOPLAST A/S;NIELSEN, BO RUD;MADSEN, NIELS JOERGEN |
发明人 |
NIELSEN, BO RUD;MADSEN, NIELS JOERGEN |
分类号 |
A61L29/08;A61L29/14 |
主分类号 |
A61L29/08 |
代理机构 |
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代理人 |
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地址 |
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