发明名称 |
PHARMACEUTICAL COMPOSITION COMPRISING CRYSTALLINE SIBUTRAMINE METHANESULFONATE HEMIHYDRATE |
摘要 |
The present invention relates to a pharmaceutical composition for treating or preventing obesity, comprising novel crystalline sibutramine methanesulfonate hemihydrate of formula (I). The crystalline sibutramine methanesulfonate hemihydrate according to the present invention has a much higher solubility in water, and enhanced stability under a high humidity/temperature condition, as compared with sibutramine hydrochloride monohydrate |
申请公布号 |
EP1545484(A4) |
申请公布日期 |
2010.01.13 |
申请号 |
EP20030799194 |
申请日期 |
2003.09.25 |
申请人 |
HANMI PHARM. CO., LTD. |
发明人 |
LEE, JAE-HEON;PARK, GHA-SEUNG;LEE, JAE-CHEOL;KIM, HAN-KYONG;CHANG, YOUNG-KIL;LEE, GWAN-SUN |
分类号 |
A61K31/13;A61K31/205;A61P3/04 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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